Prolozone is a technique that marries concepts from neural therapy, Prolotherapy, and ozone therapy. It involves injecting various combinations of procaine, anti-inflammatory medications/homeopathics, vitamins, minerals, proliferatives, and a mixture of ozone/oxygen gas into degenerated or injured joints, and into areas of pain. The result of this combination is nothing short of remarkable in that damaged tissues can be regenerated, and otherwise untreatable pain can be permanently cured.
After the numbing medicine, a small amount of gas is injected. Because of the procaine, the injection is virtually painless. It’s all oxygen, but a small amount is the highly active oxygen called ozone. Any area of pain and injury is begging for oxygen. That’s because oxygen is the most critical nutrient for energy production and healing. Without it, cells simply cannot repair. They might languish in an injured state for years, or eventually die. The oxygen alone can get the cells going. It stimulates them to excrete waste material, and promotes their ability to repair themselves and the tissues around them.
Prolozone works by providing energy-producing oxygen to the innermost parts of your joint. This is where ozone, does its magic. Ozone is a powerful stimulant of cellular growth factors, such as Transforming Growth Factor Beta (TGF-B). This powerful cytokine activates cartilage cells to produce matrix proteins necessary for the body to make the white cartilage substance.
TGF-B improves matrix protein arrangement. It protects the surface of the cartilage. It modulates the activity of enzymes that dissolve other proteins and compounds that are involved with inflammation. Injecting ozone in or around the joint stimulates tissue regeneration, a build up of antioxidant enzymes and a reduction in inflammation.
Ozone reacts almost instantly with the membranes of the cells it contacts. The oxidation of the membrane jump starts the cells. Immune cells are particularly responsive to ozone. They will produce a cascade of powerful healing chemicals called cytokines. These are the very short proteins immune cells use to talk with each other. Immune cells not only provide protection against infection, they also clean up debris and modulate inflammation.
Research has connected arthritis and chronic pain to subclinical infection. While ozone stimulates cells, when it comes into contact with microorganisms, it kills them. In other words, this non-toxic therapy can kill microbes on its own, and stimulate your immune cells to kill them as well. When delivered directly to a painful area, the combination of oxygen/ozone provides the stimulation to repair while simultaneously providing the essential oxygen to energize them.